ABSTRACT
Background Laryngeal edema is caused by the exudation of submucosal tissue fluid from the laxity of the pharynx and can lead to obstruction of the upper airway. It is commonly caused by post-extubation, drug allergy, and bacterial infection. During the current COVID-19 pandemic situation, laryngeal edema is a relatively rare but fatal complication of COVID-19. Taking measures to prevent laryngeal edema can reduce the incidence of sudden life-threatening events in the course of treatment.Case presentation: Here, we report a case in a Chinese male with COVID-19 complicated with laryngeal edema. The initial diagnosis of COVID-19 was followed by a sudden onset of inspiratory dyspnea during hospitalization. At the time of tracheal intubation, laryngeal edema was seen, and a positive bacterial culture suggested a secondary bacterial infection.Conclusion We report a rare case of laryngeal edema complicated by COVID-19. The patient recovered after prompt intubation and treatment. Close monitoring of patients' inflammation indicators and auxiliary bacterial monitoring can effectively prevent the occurrence of laryngeal edema caused by COVID-19.